The weather in Sanibel in May is very hot. The average temperatures are between 24°C and 28°C, drinking water regularly is advisable.
You can expect rain for roughly half of the month of May in Sanibel. We’re expecting roughly 8 to 15 days of rain, so your rubber boots and umbrella are going to see plenty of use this month if you’re keen on staying dry.
Our weather forecast can give you a great sense of what weather to expect in Sanibel in May 2025.
If you’re planning to visit Sanibel in the near future, we highly recommend that you review the 14 day weather forecast for Sanibel before you arrive.